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Doctor Mike
Doctor Tries To Make The Diagnosis | Doctordle
Doctor Tries To Make The Diagnosis | Doctordle
Doctor Mike
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13:21 · Jun 17, 2026
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0:00
Start playing and then just go where your mind takes you.
0:02
>> Ah, it's a dangerous place.
0:04
A once viral game called Wordle has now become medically transitioned into Doctorul.
0:11
Terrible name.
0:12
Let's see how much medicine I actually know.
0:14
Let's get started.
0:15
Be woo. 42-year-old woman presents for premenstrual breast pain.
0:21
This is like it's asking me to be Gary Brecka right now.
0:25
It's asking me to make a diagnosis of just that.
0:28
Okay, so we're going to say physiologic.
0:33
>> I think this is where you might run into trouble.
0:35
This like predetermined >> Ah, so this is interesting.
0:40
The problem is all of these are pathologic and they're all pretty serious.
0:44
I mean, it's not that it's not serious,
0:46
it's that I need to know more before I start making a diagnosis of
0:49
something serious.
0:50
>> That's not how Doctorul works.
0:51
>> But that's not how medicine should work.
0:53
There should be like a updated version of this.
0:56
Oh my god, like malingering.
0:57
Yeah, she's faking.
1:00
>> Okay, let's go.
1:01
>> Okay, so most likely diagnosis in a 12-year-old boy with rough,
1:05
raised lesions.
1:07
I would say wart, verruca vulgaris.
1:10
Oh.
1:10
>> Nailed it.
1:11
>> Okay.
1:11
>> We're a real doctor over here.
1:13
>> Warts caused by viruses.
1:15
We usually freeze them off in our office.
1:17
There are some over-the-counter treatments.
1:18
Usually not as good.
1:20
Need multiple treatments a lot of times in order to get them fully out.
1:23
But otherwise pretty benign.
1:25
A 42-year-old woman presents to her primary care physician with complaints of poor sleep
1:29
and difficulty concentrating at work.
1:31
Okay, guess where I'm going.
1:37
Damn.
1:38
She attributes her symptoms to just stress and avoids discussing specific triggers.
1:42
Poor sleep usually doesn't happen as a result of just stress.
1:47
So let's say generalized anxiety disorder.
1:50
No.
1:51
On further questioning, she admits to frequent nightmares and feeling on edge.
1:56
Well, this is getting interesting.
1:57
This is where my investigative mind goes.
1:59
So like, "Ooh, she's having frequent nightmares cuz she's taking Benadryl."
2:02
And because she's taking Benadryl so often,
2:03
she's having decreased concentration at work cuz she's feeling sleepier from the Benadryl.
2:06
Is it just depression?
2:08
No.
2:09
She recently declined a promotion
2:11
that would have required air travel citing discomfort with airports
2:14
and crowds.
2:15
Agoraphobia?
2:17
No.
2:17
She becomes visibly tense
2:18
when asked about a car accident she survived 3 years ago
2:21
and mentions that avoiding
2:22
that part of town is a post-traumatic stress disorder.
2:28
Yeah!
2:28
I mean, that's not how I would have presented it, but man,
2:30
you got to go.
2:30
That's interesting.
2:31
A newborn is assessed in the hospital for cyanosis and tachypnea.
2:36
Ah, how new is this newborn?
2:38
God, there's Like, I I would think they would reach for something crazy like
2:42
tetralogy tetralogy of Fallot.
2:45
Nope.
2:46
Supplemental oxygen does not improve symptoms.
2:50
Transposition of the great vessels.
2:52
LOOK AT THAT, BABY!
2:53
LOOK AT THAT!
2:56
>> >> AND THEY ASK ME WHY I'M KEYNOTING THE American Academy of Pediatrics
2:59
conference at the end of this year.
3:01
>> Let them know.
3:01
>> Come on, that that's a hard one.
3:03
>> That was impressive.
3:03
>> Okay, the first one is true though.
3:06
A newborn cyanosis tachypnea is tetralogy of Fallot or transposition of the great vessels.
3:11
A 40-year-old man presents with white patches on the side of his tongue.
3:15
They're probably going to want me to say thrush,
3:18
but I don't think it's thrush.
3:20
I think that they're going to say that it's not scrapeable,
3:24
which means it's leukoplakia.
3:28
>> ORAL LEUKOPLAKIA?
3:32
>> ORAL CANDIDIASIS.
3:34
>> WOW.
3:35
What about the other leukoplakia that I had?
3:38
>> DO IT!
3:40
JUST DO IT!
3:41
>> I DON'T think it's leukoplakia cuz it's a >> Do it!
3:44
>> What's the other one?
3:45
Oh, are you kidding me?
3:47
Is it chronic mucocutaneous candidiasis?
3:51
I don't know.
3:52
Physical exam shows feathery white plaques, lateral borders of the tongue.
3:55
The plaques cannot be removed.
3:57
God, is it hairy?
3:58
It might be that hairy one.
3:59
Hairy leukoplakia.
4:02
My first guess was right.
4:04
Yo, how crazy is that?
4:05
It wasn't oral leukoplakia, it was hairy leukoplakia.
4:08
That's why with no shame I would use up-to-date in a scenario like this
4:11
or my dermatological textbook.
4:13
A 30-year-old woman presents with vaginal discharge and itching.
4:17
Okay, that would be yeast infection until proven otherwise.
4:20
So, vulvovaginal vulvovaginal candidiasis.
4:25
She's sexually active with two partners and they use condoms inconsistently.
4:29
She reports her partners have no symptoms.
4:31
Okay, bacterial vaginosis, uh gonorrhea, chlamydia, trick.
4:38
Why am I missing trick?
4:39
I shouldn't be missing trick.
4:41
>> What happened there?
4:41
>> Because all of these would be tested for.
4:44
So, it's like you don't just say, "Oh, is it this one?
4:45
Is it this one?
4:46
Is it this one?"
4:47
And you keep setting the poor patient back for 10 tests.
4:49
A 30-year-old man presents with fever, muscle pains,
4:51
and chills for the past 3 days.
4:54
I mean, like influenza, right?
4:56
Let's just go influenza.
4:58
He reports that he experienced similar symptoms lasting a week a few days ago.
5:04
That doesn't make sense.
5:05
Let's skip again.
5:06
He recently returned from humanitarian trip.
5:08
He has malaria.
5:09
Malaria.
5:10
Oh my god, there's three different types of malaria.
5:14
Oh my god, babesiosis?
5:16
No, oh my god.
5:18
He denies tick exposure does not break of lice.
5:20
Typhus.
5:21
Borrelia recurrentis.
5:24
Bro, never heard of you in my life.
5:28
Never heard of you in my life.
5:30
A 30-year-old man presents with 3 days of fever, abdominal pain,
5:34
and diarrhea.
5:35
That's really broad.
5:37
You could be anything with this.
5:40
Let's go with the salmonella gastroenteritis.
5:42
He reports that the symptoms started day after attacking barbecue.
5:45
Let's call it norovirus for now.
5:47
I doubt it's norovirus though.
5:49
No.
5:50
He reports a diarrhea is initially watery but blood tinged.
5:52
I feel like it's it's salmonella.
5:55
I'm I'm going to go E. coli.
5:57
No.
5:57
He recalls eating low temperature smoked chicken recipe in
6:00
which the meat near the bone appeared undercooked.
6:03
Campylobacter?
6:05
Campylobacter, here we go.
6:10
Yeah!
6:10
The most common bacteria that you get sick from salmonella, campylobacter, E. coli.
6:16
That's what went with all of these.
6:17
I thought norovirus could be a distractor which it ended up being.
6:20
A 40-year-old man presents with rhinitis
6:22
and multiple asthma exacerbations requiring systemic corticosteroids
6:26
and hospitalizations over the year.
6:27
I know what they're going for.
6:28
They're going for some like IgA selective IgA deficiency.
6:31
No.
6:31
He reports no history of asthma exacerbation.
6:33
So, he randomly has asthma now.
6:36
Let's see if it's a COPD diagnosis.
6:39
No.
6:40
He reports new onset foot drop
6:41
as well as frequent bouts of nausea
6:43
and vomiting.
6:44
Oh my goodness.
6:45
So, he's having some sort of loss of control over his neuro system.
6:51
But, why rhinitis?
6:53
Oh, wait.
6:54
Oh, wait.
6:54
Oh, wait.
6:55
Oh, wait.
6:55
Oh, wait.
6:55
Oh, wait.
6:56
Cystic fibrosis.
7:01
Physical exam reveals rhinitis, nasal polyps, and palpable purpura.
7:05
Oh my goodness.
7:06
This feels like straight up boards question.
7:08
Is it like Buerger's disease?
7:13
Eosinophil and positive P-ANCA with normal platelets.
7:17
I'm going to go lupus just cuz sometimes you always have to think about
7:22
lupus.
7:22
It's never lupus.
7:24
A lung biopsy shows granulomatous inflammation with eosinophilic infiltration.
7:29
The nasal polyps is is definitely some sort of giveaway.
7:32
Churg-Strauss syndrome.
7:34
Yeah!
7:34
>> Yo, we got there.
7:36
>> Small to medium vessel necrotizing vasculitis, eosinophilia, asthma, granuloma.
7:42
Look at that.
7:42
T-cell B-cell activation.
7:44
A 22-year-old presents with right hand pain
7:46
and swelling that began earlier today.
7:49
>> Um.
7:49
>> Pain that started earlier today in the hand.
7:53
You know what?
7:53
This is a good one to skip cuz I don't know.
7:55
He reports sudden onset of pain when his hand struck the wall during racquetball.
8:00
Ooh, boxer's fracture.
8:05
Bro, call me Kobe.
8:06
A 63-year-old woman presents with acute chest pain
8:08
and shortness of breath
8:09
that began shortly after her boyfriend ended the relationship.
8:12
Takotsubo.
8:16
Yeah.
8:16
That's a broken heart syndrome.
8:17
Yeah, so patients like this, they start having elevations in their cardiac enzymes.
8:22
They end up going into the cath lab
8:24
because they think that there's a blockage
8:26
and they actually have no blockages
8:28
and it was temporary.
8:29
Don't break up with your boyfriend or loved one on Valentine's Day.
8:32
A 22-year-old woman presents with a several-month history of voice changes.
8:40
>> >> That rules out anything infectious because anything infectious wouldn't be several months,
8:44
otherwise there'd be an issue.
8:46
But let's go based on the age, vocal cord polyp.
8:53
>> All right.
8:53
Now, you know what?
8:54
Now you got it.
8:56
>> Yeah.
8:57
A 34-year-old woman presents with a 6-week history of crampy lower abdominal pain,
9:01
intermittent loose stools, sometimes with visible mucus.
9:05
Okay, so this is some kind of fat malabsorption.
9:09
Let's go with celiac.
9:12
She returned 8 weeks ago from a 3-month volunteer placement in rural Guatemala where
9:16
she reports drinking untreated well water on several occasions,
9:20
eating street food regularly.
9:21
I don't think it's one of these acute ones.
9:23
It's some kind of parasite.
9:25
Let's say tapeworm.
9:26
On closer question, she says bloody diarrhea.
9:29
Uh.
9:30
Hookworm.
9:31
Stool microscopy reveals motile trophozoites containing ingested red blood cells
9:37
and colonoscopy shows scattered flask-shaped mucosal ulcerations.
9:41
Leptospirosis?
9:43
No.
9:43
Right upper quadrant ultrasound performed to investigate a dull aching sensation she mentions revealing
9:47
a 5-cm hypoechoic lesions in the right hepatic lobe.
9:52
It's some kind of freaking protozoan and I can't put my finger on it.
9:56
Shigella?
9:58
She started metronidazole followed by a luminal agent and her symptoms resolved.
10:02
It's some kind of worm.
10:03
Trichodosis is my best guess.
10:05
Nope.
10:06
Entamoeba histolytica.
10:08
That's a good one.
10:09
It's a pathological protozoan.
10:11
I said I It's a protozoa of some sort.
10:14
I said it like a hundred times, but we just don't see this here.
10:18
Uh A 58-year-old man presents to the emergency department with nausea
10:21
and chest pain that began
10:23
when eating Thanksgiving dinner.
10:25
All right, we're going to have to assume heart attack.
10:27
He has a history of hypertension, high risk, hyperlipidemia, high cholesterol,
10:31
high risk. 30 pack-year smoking history, very high risk.
10:34
Let's say non-ST elevation MI.
10:37
Physical exam reveals diaphoresis and mild tachycardia.
10:40
So, he has a fast heart rate and he's sweating.
10:43
These are not very valuable.
10:44
I mean, are they really going for dissecting uh aortic dissection?
10:49
Like, that's aggressive.
10:50
Nope.
10:51
ECG shows diffuse ST depression.
10:54
I mean, if it was elevations, I would say like maybe myocarditis.
10:59
Pulmonary embolism?
11:01
Serial troponins are negative.
11:02
So, he's not having a heart attack.
11:03
He's not having a pulmonary embolism,
11:05
but he's having nausea and he's having chest pain.
11:08
Oh my god, is this some kind of like lung cancer presenting tumor?
11:13
Small cell carcinoma?
11:15
The patient reports that the pain occurs with both exertion
11:17
and at rest and has been increasing frequency over the past week.
11:21
He said it happened during Thanksgiving dinner.
11:23
Oh, unstable angina.
11:25
Oh my god.
11:26
Oh my god, this is so embarrassing.
11:30
Yeah.
11:30
I should have gotten that.
11:31
My bad.
11:31
My bad.
11:32
A 45-year-old man presents to the emergency room with fever, chills, headache,
11:35
painful groin swelling, and weakness.
11:38
Okay, I'm going to say prostatitis.
11:40
Wrong.
11:41
He recently returned from a camping trip in New Mexico where he slept without
11:44
a tent for multiple days.
11:48
Jesus.
11:48
Oh, they're going to say it's some kind of bug bite.
11:51
Blastomycosis.
11:54
No, on physical exam there are firm,
11:55
non-tender lymph nodes in the inguinal region
11:57
that are not showing any warmth
11:57
or tenderness.
11:58
Yeah, I know.
11:59
Something that bit him.
12:00
What bites in Mexico?
12:01
Coccidioidomycosis?
12:03
No.
12:04
Leukocytosis.
12:05
Okay, his white count He doesn't have a lot of platelets.
12:08
Uh shh.
12:13
God, what is it?
12:14
Over the next 3 days the buboes come out and become suppurative.
12:17
Oh my god, they're going to say it's the bubonic plague.
12:20
IT'S THE BUBONIC PLAGUE.
12:21
>> OH, THAT'S THE BEST.
12:23
>> I mean, how was I supposed to I bubonic plague, man. >> in the clinic?
12:28
>> Yeah, last week. 40-year-old man presents with pain
12:30
and swelling over his right knee. 4-year-old is a bit young for OA.
12:35
Let's go rheumatoid arthritis, even though it's not the most likely cause.
12:39
He denies instability or limited range of motion.
12:41
Okay.
12:42
So, pain and swelling over his right knee.
12:45
If he doesn't have instability, we know that there's no tears of anything.
12:48
There's no limitations in range of motion, which is good.
12:51
Prepatellar bursitis.
12:53
Look at that.
12:54
Two guesses.
12:55
A 26-year-old man presents with crampy abdominal pain
12:57
and bloody diarrhea for several months.
13:00
I'm going ulcerative colitis until proven otherwise.
13:03
>> And that's it.
13:05
That's it.
13:07
>> How about reacting to some of the world's rarest diseases?
13:10
Click here to check that out, and as always, stay happy and healthy.
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